对血液制品S/D病毒灭活方法的验证Verification of Virus Inactivation in Blood Products by S/D Method
周铁群,邱平,王剑锋,戴斌
摘要(Abstract):
以水疱性口炎病毒(VSV)为指示病毒,验证S/D法处理对凝血因子Ⅷ、纤维蛋白原和凝血酶原复合物三种血液制品的病毒灭活效果。结果该法对三种制品中的VSV灭活能力分别为5.13、5.38和3.25LogTCID50/0.1ml以上(均为可检测限)。表明S/D方法对VSV等脂包膜病毒可起到有效的灭活作用。
关键词(KeyWords): 血液制品;水疱性口炎病毒;S/D(Solvent/Detergent)灭活法
基金项目(Foundation):
作者(Author): 周铁群,邱平,王剑锋,戴斌
Email:
DOI: 10.13200/j.cjb.1995.03.107.zhoutq.005
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