张丹;杨春;

• 1:广州军区武汉总医院核医学科
• 2:重庆医科大学病原生物学教研室
• 3:重庆医科大学神经科学研究中心

摘要(Abstract)：

甘丙肽受体2(Galanin receptor 2,GalR2)是一种G蛋白偶联受体,其mRNA集中分布于下丘脑、海马、杏仁核、皮质部分区域和背根神经节。甘丙肽(Galanin)与GalR2结合,参与调节机体摄食、认知、学习与记忆、痛觉、情绪反应、炎症、肿瘤等多种生理病理过程。GalR2是治疗阿尔茨海默病、抑郁和焦虑、疼痛、代谢综合征及肿瘤等疾病潜在药物作用的靶点。本文就GalR2受体的结构、分布及其与疾病的相关性作一简要综述。

关键词(KeyWords)： 受体,促生长激素神经肽,2型;疾病

Abstract:

Keywords:

基金项目(Foundation):

作者(Author): 张丹;杨春;

Email:

DOI: 10.13200/j.cjb.2012.01.131.zhangd.006

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